Prestazin

A derivative of diphenylmethane, it has moderate anxiolytic activity, and also has a sedative, antiemetic, antihistamine, moderate analgesic and m-anticholinergic, antispasmodic effect. Blocks central m-cholinergic receptors and histamine H1 receptors and inhibits the activity of certain subcortical zones. Does not cause mental dependence or addiction. Has a positive effect on cognitive abilities, improves memory and attention. Relaxes skeletal and smooth muscles, has bronchodilator and analgesic effects, and a moderate inhibitory effect on gastric secretion.

Each film-coated tablet contains:

• Hydroxyzine hydrochloride 25 mg.

• for the relief of anxiety, psychomotor agitation, feelings of internal tension, increased irritability in neurological, mental (including generalized anxiety, adaptation disorders) and somatic diseases, chronic alcoholism; withdrawal syndrome in chronic alcoholism, accompanied by psychomotor agitation;
• as a sedative during premedication;
• for skin itching (as symptomatic therapy);
• for depression;
• for insomnia;
• with neurosis;
• during menopause;
• for epilepsy.

Directions for use and dosage:
The drug is taken orally. It is recommended to begin treatment with low doses of the drug and gradually increase to the optimal dose, adjusting it in accordance with the patient's response to therapy.
For the symptomatic treatment of itching of allergic origin: from 25 to 100 mg (1 to 4 tablets) per day.
For premedication in surgical practice: once from 25 to 100 mg (1 to 4 tablets) at night, before surgery.
The maximum daily dose of the drug for adults and children weighing more than 40 kg is 100 mg.

 Children: For the symptomatic treatment of itching of allergic origin:
Over the age of 12 years (with body weight over 40 kg): from 25 to 100 mg (1 to 4 tablets) per day.
At the age of 9 to 12 years (with body weight from 28 to 40 kg): from 25 to 75 mg (from 1 to 3 tablets) per day.
Ages 7 to 9 years (body weight 23 to 28 kg): 25 to 50 mg (1 to 2 tablets) per day.
At the age of 4 to 7 years (with body weight from 17 to 23 kg): from 25 to 37.5 mg (from 1 to 1.5 tablets) per day.
At the age of 3 to 4 years (with body weight from 12.5 to 17 kg): from 12.5 to 25 mg (from ½ to 1 tablet) per day.
For children, the dose is determined based on body weight at a rate of 1 mg/kg/day to a maximum of 2 mg/kg/day, in divided doses.